Royal Air Force Typhoon FGR4s have operated alongside French aircraft in a joint strike on an hidden munitions depot in Syria used by the IS group, according to the UK's MoD.
The facility, identified by surveillance, was thought to be containing munitions and bombs, the statement said, and was positioned in hills just to the north of Palmyra in central Syria.
"The RAF jets utilized Paveway IV guided bombs to hit a number of entry passages providing entry to the depot... early reports suggest the target was engaged successfully," the MoD said.
There was no sign of any harm to civilians in the operation conducted Saturday night and all the aircraft returned safely, the defence officials confirmed.
The British jets were assisted by a Voyager aerial refuelling aircraft.
IS - also known as Daesh - established extremist governance over significant areas in both Syria and Iraq before its territorial defeat in 2019.
"This action shows British leadership, and commitment to work closely with our allies, to eliminate any resurgence of the terrorist group and their violent and radical beliefs in the Middle East," the British Defence Secretary the Defence Secretary remarked.
RAF aircraft have conducted surveillance missions over Syrian airspace to "prevent any attempted resurgence" of Islamic State subsequent to its routing at the Baghuz confrontation in the year 2019, the MoD reported.
"I want to thank the personnel of British forces who took part in this strike for their skill and their bravery," Healey commented. "They were part of a great many UK service members deployed over the holidays. This mission, to remove militants who threaten our safety, shows how our armed forces are ready to step up, continuously, protecting the UK within its borders and influential overseas."
In December, the United States armed forces carried out what it termed a "large-scale strike" on Islamic State objectives in Syria, following an ambush resulted in the deaths of two American soldiers and a civilian linguist in the Palmyra area.
The United Nations reports Islamic State still maintains roughly 5-7 thousand militants in both countries.
